Academy of Medical Sciences of Islamic Republic of IranArchives of Iranian Medicine1029-29771322010A Giant Polypoid Basal Cell Carcinoma of the Lower Extremity153155ENFarhadHandjaniDepartment of Dermatology, Shiraz University of Medical Sciences, Shiraz, Iran. hanjanif@yahoo.comShimaShahbazDepartment of Dermatology, Shiraz University of Medical Sciences, Shiraz, Iran.FatemehSari-AslaniDepartment of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran.ShahinAghaeiDepartment of Dermatology, Jahrom University of Medical Sciences, Jahrom, Iran.Ali AkbarAli-ZadehDepartment of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran.0014010132/AIM.0014Less than 1% of basal cell carcinomas are giant basal cell carcinomas. Giant basal cell carcinomas are rare. They preferentially involve the trunk and are commonly associated with neglect. Giant basal cell carcinomas of 10 cm or greater are associated with a high rate of metastasis. We report a case of giant basal cell carcinoma of the leg which is not associated with neglect and no signs of metastasis, despite being more than 10 cm in diameter. The present paper includes a brief review of the literature.